IFT140

IFT140
Identifiers
Aliases	IFT140, MZSDS, SRTD9, WDTC2, c305C8.4, c380F5.1, gs114, intraflagellar transport 140, RP80
External IDs	OMIM: 614620; MGI: 2146906; HomoloGene: 40979; GeneCards: IFT140; OMA:IFT140 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,612,072 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	25,318,469 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; left testis; ; right testis; ; ventricular zone; ; anterior pituitary; ; stromal cell of endometrium; ; olfactory zone of nasal mucosa; ; bronchial epithelial cell;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; spermatocyte; ; spermatid; ; seminiferous tubule; ; tibiofemoral joint; ; human fetus; ; blood; ; external carotid artery; ; internal carotid artery; ; medullary collecting duct;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function; protein binding;
Cellular component	cytoplasm; ciliary basal body; centrosome; cell projection; photoreceptor outer segment; intraciliary transport particle A; photoreceptor connecting cilium; microtubule organizing center; ciliary tip; axoneme; cytoskeleton; cilium; non-motile cilium;
Biological process	renal system development; cilium assembly; limb morphogenesis; intraciliary transport; skeletal system morphogenesis; photoreceptor cell outer segment organization; neural tube patterning; regulation of smoothened signaling pathway; heart development; determination of left/right symmetry; cell projection organization; retina development in camera-type eye; protein localization to cilium; regulation of cilium assembly; intraciliary retrograde transport; embryonic camera-type eye development; intraciliary transport involved in cilium assembly; embryonic digit morphogenesis; embryonic cranial skeleton morphogenesis; non-motile cilium assembly; embryonic brain development;
	Sources:Amigo / QuickGO
Orthologs
	9742
	106633
	ENSG00000187535
	ENSMUSG00000024169
	Q96RY7
	E9PY46
	NM_014714
	NM_134126
	NP_055529
	NP_598887
	Wikidata
View/Edit Human	View/Edit Mouse

IFT140, Intraflagellar transport 140 homolog, is a protein that in humans is encoded by the IFT140 gene. The gene product forms a core component of IFT-A complex which is indipensible for retrograde intraflagellar transport within the primary cilium.