Hyaluronan synthase
| Hyaluronan synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Chlorella virus hyaluronan synthase with the manganese ion shown as a cyan sphere. | |||||||||
| Identifiers | |||||||||
| EC no. | 2.4.1.212 | ||||||||
| CAS no. | 39346-43-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Hyaluronan synthases (HAS) are membrane-bound enzymes that use UDP-α-N-acetyl-D-glucosamine and UDP-α-D-glucuronate as substrates to produce the glycosaminoglycan hyaluronan at the cell surface and extrude it through the membrane into the extracellular space.