HSPA4

HSPA4
Identifiers
Aliases	HSPA4, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY, heat shock protein family A (Hsp70) member 4
External IDs	OMIM: 601113; MGI: 1342292; HomoloGene: 1624; GeneCards: HSPA4; OMA:HSPA4 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	133,106,449 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	53,191,284 bp
RNA expression pattern
	Top expressed in
	gonad; ; gingival epithelium; ; islet of Langerhans; ; right testis; ; left testis; ; mucosa of pharynx; ; stromal cell of endometrium; ; amniotic fluid; ; tendon of biceps brachii; ; tonsil;
	Top expressed in
	otic placode; ; saccule; ; tail of embryo; ; genital tubercle; ; otic vesicle; ; primitive streak; ; epiblast; ; Ileal epithelium; ; trigeminal ganglion; ; endothelial cell of lymphatic vessel;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding;
Cellular component	cytoplasm; cytosol; extracellular exosome; nucleus;
Biological process	response to unfolded protein; protein insertion into mitochondrial outer membrane; chaperone-mediated protein complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	3308
	15525
	ENSG00000170606
	ENSMUSG00000020361
	P34932
	Q61316; Q3U2G2
	NM_198431; NM_002154
	NM_008300
	NP_002145
	NP_032326
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock 70 kDa protein 4 is a protein that in humans is encoded by the HSPA4 gene.

The protein encoded by this gene was originally suggested to be a member of the heat shock protein 70 family. However it is now known that human HSPA4 is an equivalent to mouse the Apg-2 protein and is a member of the Hsp110 family.