HRK (gene)

HRK
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2L58, 2L5B
Identifiers
Aliases	HRK, DP5, HARAKIRI, harakiri, BCL2 interacting protein
External IDs	OMIM: 603447; MGI: 1201608; HomoloGene: 136405; GeneCards: HRK; OMA:HRK - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	116,881,441 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	118,327,543 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; endothelial cell; ; pancreatic ductal cell; ; gonad; ; testicle; ; Brodmann area 23; ; hippocampus proper; ; prefrontal cortex; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; Rostral migratory stream; ; trigeminal ganglion; ; striatum of neuraxis; ; primary visual cortex; ; temporal lobe; ; nucleus accumbens; ; Region I of hippocampus proper; ; dorsal striatum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; membrane; mitochondrion;
Biological process	regulation of apoptotic process; positive regulation of protein homooligomerization; positive regulation of release of cytochrome c from mitochondria; positive regulation of apoptotic process; apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	8739
	12123
	ENSG00000135116
	ENSMUSG00000046607
	O00198
	P62816
	NM_003806
	NM_007545
	NP_003797
	NP_031571
	Wikidata
View/Edit Human	View/Edit Mouse

Activator of apoptosis harakiri is a protein that in humans is encoded by the HRK gene.