HOMER1

HOMER1
Identifiers
Aliases	HOMER1, HOMER, HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1, homer scaffolding protein 1, homer scaffold protein 1
External IDs	OMIM: 604798; MGI: 1347345; HomoloGene: 3155; GeneCards: HOMER1; OMA:HOMER1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	79,514,134 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	93,541,637 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle temporal gyrus; ; orbitofrontal cortex; ; Skeletal muscle tissue of biceps brachii; ; endothelial cell; ; Epithelium of choroid plexus; ; right ventricle; ; frontal pole; ; vastus lateralis muscle; ; superior frontal gyrus;
	Top expressed in
	dorsal striatum; ; triceps brachii muscle; ; temporal muscle; ; olfactory tubercle; ; superior frontal gyrus; ; nucleus accumbens; ; sternocleidomastoid muscle; ; prefrontal cortex; ; muscle of thigh; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane transporter binding; signaling adaptor activity; protein binding; G protein-coupled glutamate receptor binding;
Cellular component	cytoplasm; postsynaptic membrane; membrane; postsynaptic density; plasma membrane; apical part of cell; synapse; axon; cell junction; Z discdkac; neuron projection; costamere; postsynapse; cytosol; neuron spine; cell projection; dendritic spine; dendrite; glutamatergic synapse; postsynaptic cytosol;
Biological process	phospholipase C-activating G protein-coupled glutamate receptor signaling pathway; positive regulation of signal transduction; behavioral response to cocaine; skeletal muscle contraction; regulation of calcium ion import; response to calcium ion; chemical homeostasis within a tissue; skeletal muscle fiber development; positive regulation of calcium ion transport; chemical synaptic transmission; regulation of cation channel activity; regulation of store-operated calcium entry; protein tetramerization; regulation of synaptic transmission, glutamatergic; regulation of dendritic spine maintenance; G protein-coupled glutamate receptor signaling pathway; regulation of postsynaptic neurotransmitter receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	9456
	26556
	ENSG00000152413
	ENSMUSG00000007617
	Q86YM7
	Q9Z2Y3
	NM_004272; NM_001277077; NM_001277078
	NM_001284189; NM_011982; NM_147176; NM_152134; NM_001347598
	NP_001264006; NP_001264007; NP_004263
	NP_001271118; NP_001334527; NP_036112; NP_671705; NP_687036
	Wikidata
View/Edit Human	View/Edit Mouse

Homer protein homolog 1 or Homer1 is a neuronal protein that in humans is encoded by the HOMER1 gene. Other names are Vesl and PSD-Zip45.