H2AFJ

H2AJ
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4EDU
Identifiers
Aliases	H2AJ, H2AFJ, H2A.J histone, H2A histone family member J
External IDs	MGI: 3606192; HomoloGene: 128575; GeneCards: H2AJ; OMA:H2AJ - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	14,778,002 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	136,787,072 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; olfactory zone of nasal mucosa; ; mucosa of transverse colon; ; tibial arteries; ; left coronary artery; ; thoracic aorta; ; right coronary artery; ; ascending aorta; ; Descending thoracic aorta;
	Top expressed in
	Paneth cell; ; internal carotid artery; ; external carotid artery; ; lacrimal gland; ; crypt of lieberkuhn of small intestine; ; fossa; ; condyle; ; blood; ; hair follicle; ; submandibular gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein heterodimerization activity; DNA binding; molecular function;
Cellular component	extracellular exosome; chromosome; nucleosome; nucleus;
Biological process	chromatin organization; biological process;
	Sources:Amigo / QuickGO
Orthologs
	55766
	232440
	ENSG00000246705
	ENSMUSG00000060032
	Q9BTM1
	Q8R1M2
	NM_018267; NM_177925
	NM_177688
	NP_808760
	NP_808356
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H2A.J is a protein that in humans is encoded by the H2AFJ gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member.