Glycerophosphorylcholine

Glycerophosphorylcholine
Clinical data
ATC code	N07AX02 (WHO) ;
Legal status
Legal status	In general: Over-the-counter (OTC);
Identifiers
	IUPAC name [(2R)-2,3-Dihydroxypropyl] 2-trimethylazaniumylethyl phosphate;
CAS Number	28319-77-9 ;
PubChem CID	657272;
ChemSpider	571409 ;
UNII	60M22SGW66;
ChEBI	CHEBI:55397 ;
ChEMBL	ChEMBL1567463 ;
CompTox Dashboard (EPA)	DTXSID70951010 ;
ECHA InfoCard	100.044.496
Chemical and physical data
Formula	C8H20NO6P
Molar mass	257.223 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [O-]P(=O)(OC[C@H](O)CO)OCC[N+](C)(C)C;
	InChI InChI=1S/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/m1/s1 ; Key:SUHOQUVVVLNYQR-MRVPVSSYSA-N ;
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L-α-Glycerophosphorylcholine (alpha-GPC, choline alfoscerate, sn-glycero-3-phosphocholine) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor which has been investigated for its potential for the treatment of Alzheimer's disease and other dementias.

Alpha-GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of acetylcholine. It is a non-prescription drug in most countries. The FDA determined that intake of no more than 196.2 mg/person/day is considered generally recognized as safe (GRAS).

Clinical data


ATC code	N07AX02 (WHO)
Legal status
Legal status	In general: Over-the-counter (OTC)
Identifiers
IUPAC name [(2R)-2,3-Dihydroxypropyl] 2-trimethylazaniumylethyl phosphate
CAS Number	28319-77-9^N
PubChem CID	657272
ChemSpider	571409^Y
UNII	60M22SGW66
ChEBI	CHEBI:55397^Y
ChEMBL	ChEMBL1567463^N
CompTox Dashboard (EPA)	DTXSID70951010
ECHA InfoCard	100.044.496
Chemical and physical data
Formula	C₈H₂₀NO₆P
Molar mass	257.223 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES [O-]P(=O)(OC[C@H](O)CO)OCC[N+](C)(C)C
InChI InChI=1S/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/m1/s1^Y Key:SUHOQUVVVLNYQR-MRVPVSSYSA-N^Y
^NY (what is this?) (verify)