GTF2H4

GTF2H4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5IY9, 5IVW, 5IY7, 5IY8, 5IY6
Identifiers
Aliases	GTF2H4, general transcription factor IIH, polypeptide 4, 52kDa, P52, TFB2, TFIIH, general transcription factor IIH subunit 4
External IDs	OMIM: 601760; MGI: 1338799; HomoloGene: 7090; GeneCards: GTF2H4; OMA:GTF2H4 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	30,914,106 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	35,984,631 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; pituitary gland; ; right hemisphere of cerebellum; ; anterior pituitary; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; body of uterus; ; tibial arteries; ; right coronary artery; ; apex of heart;
	Top expressed in
	thymus; ; otic vesicle; ; otic placode; ; spermatocyte; ; epiblast; ; saccule; ; mandibular prominence; ; abdominal wall; ; maxillary prominence; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein kinase activity; ATP-dependent activity, acting on DNA; DNA-binding transcription factor activity; DNA helicase activity; protein binding; RNA polymerase II CTD heptapeptide repeat kinase activity; double-stranded DNA binding; ATPase activator activity; RNA polymerase II general transcription initiation factor activity;
Cellular component	nucleoplasm; transcription factor TFIIH holo complex; core TFIIH complex portion of holo TFIIH complex; transcription factor TFIIH core complex; nucleus; transcription factor TFIID complex; nuclear speck;
Biological process	termination of RNA polymerase I transcription; regulation of transcription, DNA-templated; phosphorylation of RNA polymerase II C-terminal domain; transcription initiation from RNA polymerase I promoter; transcription elongation from RNA polymerase II promoter; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; transcription, DNA-templated; cellular response to DNA damage stimulus; global genome nucleotide-excision repair; transcription-coupled nucleotide-excision repair; transcription initiation from RNA polymerase II promoter; nucleotide-excision repair, DNA incision; DNA repair; nucleotide-excision repair; nucleotide-excision repair, preincision complex stabilization; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, DNA incision, 5'-to lesion; DNA duplex unwinding; positive regulation of ATP-dependent activity; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision, 3'-to lesion; transcription elongation from RNA polymerase I promoter;
	Sources:Amigo / QuickGO
Orthologs
	2968
	14885
	ENSG00000213780
	ENSMUSG00000001524
	Q92759
	O70422
	NM_001517
	NM_010364
	NP_001508
	NP_034494
	Wikidata
View/Edit Human	View/Edit Mouse

General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.