GTF2E1

GTF2E1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1VD4, 2JTX, 2RNQ, 2RNR, 5IY9, 5IYC, 5IYD, 5IY7, 5IYA, 5IY6, 5IYB, 5IY8
Identifiers
Aliases	GTF2E1, FE, TF2E1, TFIIE-A, general transcription factor IIE subunit 1
External IDs	OMIM: 189962; MGI: 1921447; HomoloGene: 38062; GeneCards: GTF2E1; OMA:GTF2E1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	120,783,069 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	37,360,151 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; testicle; ; gonad; ; periodontal fiber; ; sperm; ; monocyte; ; stromal cell of endometrium; ; right adrenal cortex; ; islet of Langerhans;
	Top expressed in
	hand; ; superior cervical ganglion; ; otic vesicle; ; endocardial cushion; ; primitive streak; ; medial ganglionic eminence; ; abdominal wall; ; atrioventricular valve; ; iris; ; trigeminal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; sequence-specific DNA binding; protein binding; RNA polymerase II complex binding; TFIIH-class transcription factor complex binding; RNA polymerase II general transcription initiation factor activity;
Cellular component	nucleus; nucleoplasm; transcription factor TFIID complex; cytosol; transcription preinitiation complex; transcription factor TFIIE complex;
Biological process	regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; transcription initiation from RNA polymerase II promoter; snRNA transcription by RNA polymerase II; viral process; transcription open complex formation at RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologs
	2960
	74197
	ENSG00000153767
	ENSMUSG00000022828
	P29083
	Q9D0D5
	NM_005513
	NM_028812; NM_001355727
	NP_005504
	NP_083088; NP_001342656
	Wikidata
View/Edit Human	View/Edit Mouse

General transcription factor IIE subunit 1 (GTF2E1), also known as transcription initiation factor IIE subunit alpha (TFIIE-alpha), is a protein that in humans is encoded by the GTF2E1 gene.