GRIA3

GRIA3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LSW, 3LSX
Identifiers
Aliases	GRIA3, GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94, glutamate ionotropic receptor AMPA type subunit 3, MRXSW
External IDs	OMIM: 305915; MGI: 95810; HomoloGene: 37353; GeneCards: GRIA3; OMA:GRIA3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	123,490,915 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	40,767,478 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle temporal gyrus; ; primary visual cortex; ; entorhinal cortex; ; postcentral gyrus; ; superior frontal gyrus; ; Brodmann area 9; ; right frontal lobe; ; prefrontal cortex; ; hippocampus proper;
	Top expressed in
	subiculum; ; anterior amygdaloid area; ; olfactory tubercle; ; dorsal striatum; ; lateral septal nucleus; ; nucleus accumbens; ; lateral geniculate nucleus; ; facial motor nucleus; ; lobe of cerebellum; ; prefrontal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	ion channel activity; ionotropic glutamate receptor activity; extracellularly glutamate-gated ion channel activity; AMPA glutamate receptor activity; excitatory extracellular ligand-gated ion channel activity; amyloid-beta binding; signaling receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; endocytic vesicle membrane; postsynaptic membrane; membrane; synapse; cell junction; AMPA glutamate receptor complex; plasma membrane; parallel fiber to Purkinje cell synapse;
Biological process	glutamate receptor signaling pathway; ion transport; ion transmembrane transport; ionotropic glutamate receptor signaling pathway; transport; excitatory postsynaptic potential; regulation of postsynaptic membrane potential; regulation of NMDA receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	2892
	53623
	ENSG00000125675
	ENSMUSG00000001986
	P42263
	Q9Z2W9
	NM_181894; NM_000828; NM_001256743; NM_007325
	NM_001281929; NM_016886; NM_001290451; NM_001358361
	NP_000819; NP_001243672; NP_015564
	NP_001268858; NP_001277380; NP_058582; NP_001345290
	Wikidata
View/Edit Human	View/Edit Mouse

Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene.