GOLGA4

GOLGA4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1R4A, 1UPT
Identifiers
Aliases	GOLGA4, CRPF46, GCP2, GOLG, MU-RMS-40.18, golgin A4, Trans-GolgiI p230, Golgin 245, p230
External IDs	OMIM: 602509; MGI: 1859646; HomoloGene: 68224; GeneCards: GOLGA4; OMA:GOLGA4 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	37,366,879 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	118,582,519 bp
RNA expression pattern
	Top expressed in
	glutes; ; jejunal mucosa; ; biceps brachii; ; Skeletal muscle tissue of rectus abdominis; ; thoracic diaphragm; ; right ventricle; ; Skeletal muscle tissue of biceps brachii; ; myocardium of left ventricle; ; cartilage tissue; ; triceps brachii muscle;
	Top expressed in
	muscle of thigh; ; digastric muscle; ; Paneth cell; ; triceps brachii muscle; ; soleus muscle; ; vastus lateralis muscle; ; plantaris muscle; ; temporal muscle; ; Rostral migratory stream; ; tibialis anterior muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	GTPase binding; protein binding;
Cellular component	cytoplasm; Golgi membrane; trans-Golgi network; Golgi apparatus; extracellular exosome; intracellular membrane-bounded organelle; membrane; cytosol;
Biological process	positive regulation of axon extension; vesicle-mediated transport; Golgi to plasma membrane protein transport;
	Sources:Amigo / QuickGO
Orthologs
	2803
	54214
	ENSG00000144674
	ENSMUSG00000038708
	Q13439; Q49A56
	Q91VW5
	NM_001172713; NM_002078
	NM_018748
	NP_001166184; NP_002069; NP_001166184.1; NP_002069.2
	NP_061218
	Wikidata
View/Edit Human	View/Edit Mouse

Golgin subfamily A member 4 is a protein that in humans is encoded by the GOLGA4 gene.

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins are a family of proteins, of which the protein encoded by this gene is a member, that are localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternative splice variants have been described but their full-length nature has not been determined.