GMDS (gene)

GMDS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1T2A
Identifiers
Aliases	GMDS, GMD, SDR3E1, GDP-mannose 4,6-dehydratase
External IDs	OMIM: 602884; MGI: 1891112; HomoloGene: 75968; GeneCards: GMDS; OMA:GMDS - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	2,245,605 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	32,522,723 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; mucosa of transverse colon; ; Descending thoracic aorta; ; rectum; ; ascending aorta; ; duodenum; ; minor salivary glands; ; palpebral conjunctiva; ; right coronary artery; ; mucosa of sigmoid colon;
	Top expressed in
	Paneth cell; ; epithelium of stomach; ; large intestine; ; colon; ; duodenum; ; jejunum; ; left colon; ; ileum; ; rib; ; epithelium of small intestine;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; NADP+ binding; lyase activity; GDP-mannose 4,6-dehydratase activity; identical protein binding;
Cellular component	cytosol; extracellular exosome; cytoplasm;
Biological process	GDP-mannose metabolic process; 'de novo' GDP-L-fucose biosynthetic process; Notch signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2762
	218138
	ENSG00000112699
	ENSMUSG00000038372
	O60547
	Q8K0C9
	NM_001253846; NM_001500
	NM_146041
	NP_001240775; NP_001491
	NP_666153
	Wikidata
View/Edit Human	View/Edit Mouse

GDP-mannose 4,6 dehydratase is an enzyme that in humans is encoded by the GMDS gene.