GALNT14

GALNT14
Identifiers
Aliases	GALNT14, GALNT15, GalNac-T10, GalNac-T14, polypeptide N-acetylgalactosaminyltransferase 14
External IDs	OMIM: 608225; MGI: 1918935; HomoloGene: 56997; GeneCards: GALNT14; OMA:GALNT14 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	31,155,202 bp
RNA expression pattern
	Top expressed in
	kidney tubule; ; renal medulla; ; human kidney; ; nasal epithelium; ; glomerulus; ; lateral nuclear group of thalamus; ; metanephric glomerulus; ; endothelial cell; ; epithelium of esophagus; ; periodontal fiber;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glycosyltransferase activity; transferase activity; metal ion binding; carbohydrate binding; polypeptide N-acetylgalactosaminyltransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; membrane; Golgi membrane;
Biological process	protein glycosylation; O-glycan processing;
	Sources:Amigo / QuickGO
Orthologs
	79623
	71685
	ENSG00000158089
	n/a
	Q96FL9
	Q8BVG5
NM_001253826; NM_001253827; NM_024572; NM_001329095; NM_001329096;
	NM_001329097
	NM_027864
NP_001240755; NP_001240756; NP_001316024; NP_001316025; NP_001316026;
	NP_078848
	NP_082140
	Wikidata
View/Edit Human	View/Edit Mouse

Polypeptide N-acetylgalactosaminyltransferase 14 is an enzyme that in humans is encoded by the GALNT14 gene.

GALNT14 (EC 2.4.1.41) belongs to a large subfamily of glycosyltransferases residing in the Golgi apparatus. GALNT enzymes catalyze the first step in the O-glycosylation of mammalian proteins by transferring N-acetyl-D-galactosamine (GalNAc) to peptide substrates.[supplied by OMIM]

SNPs on GALNT14 have been shown to be associated to the chemotherapy responses of patients with advanced hepatocellular carcinoma.