GABPA

GABPA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AWC, 1SXD, 2JUO
Identifiers
Aliases	GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07, GA binding protein transcription factor alpha subunit, GA binding protein transcription factor subunit alpha
External IDs	OMIM: 600609; MGI: 95610; HomoloGene: 1543; GeneCards: GABPA; OMA:GABPA - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	25,772,460 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	84,660,667 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ventricular zone; ; ganglionic eminence; ; thymus; ; skin of arm; ; synovial membrane; ; gonad; ; smooth muscle tissue; ; synovial joint; ; germinal epithelium;
	Top expressed in
	genital tubercle; ; tail of embryo; ; Paneth cell; ; dermis; ; abdominal wall; ; migratory enteric neural crest cell; ; atrioventricular valve; ; vas deferens; ; left lung lobe; ; Gonadal ridge;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription coactivator activity; chromatin binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleus;
Biological process	cell differentiation; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; mitochondrion organization; in utero embryonic development; negative regulation of transcription by RNA polymerase II; negative regulation of megakaryocyte differentiation; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; positive regulation of gene expression; cellular response to dopamine; blastocyst formation;
	Sources:Amigo / QuickGO
Orthologs
	2551
	14390
	ENSG00000154727
	ENSMUSG00000008976
	Q06546; Q8IYS3
	Q00422
	NM_001197297; NM_002040
	NM_008065
	NP_001184226; NP_002031; NP_002031.2
	NP_032091
	Wikidata
View/Edit Human	View/Edit Mouse

GA-binding protein alpha chain is a protein that in humans is encoded by the GABPA gene.