Frederick Pei Li

Frederick Pei Li
Born(1940-05-07)May 7, 1940
DiedJune 12, 2015(2015-06-12) (aged 75)
Alma mater
Known forLi-Fraumeni syndrome
Scientific career
Institutions

Frederick Pei Li (Chinese: 李沛; May 7, 1940 – June 12, 2015) was a Chinese-American physician. He is most famous for his discovery, together with his colleague Joseph Fraumeni, of Li–Fraumeni syndrome, which is caused by germline mutations of the p53 tumor suppressor gene and genetically predisposes families to high rates of cancer.

Li was born in China and raised in the United States, where he worked at the National Cancer Institute as a pioneer in cancer research and later as a professor at Harvard Medical School. He died in 2015 of Alzheimer's disease.