Fred McLafferty

Fred W. McLafferty
Born(1923-05-11)May 11, 1923
DiedDecember 26, 2021(2021-12-26) (aged 98)
Alma materUniversity of Nebraska (BS, 1943 MS, 1947)
Cornell University (PhD, 1950)
University of Iowa (PostDoc)
Known forGas chromatography–mass spectrometry

Electron-capture dissociation

McLafferty rearrangement
AwardsACS Award in Chemical Instrumentation (1971)
Fisher Award (1981)
Member of the National Academy of Sciences (1982)
William H. Nichols Medal (1984)
Oesper Award (1985)
Sir J.J. Thomson Gold Medal (1985)
Field and Franklin Award (1989)
ASMS Distinguished Contribution in Mass Spectrometry Award (2003)
Lavoisier Medal (2004)
Scientific career
FieldsChemist
InstitutionsPurdue University
Cornell University
Doctoral students
External videos
“A Conversation with Fred W. McLafferty”, Cornell University, 2006, 90 minute video

Fred Warren McLafferty (May 11, 1923 − December 26, 2021) was an American chemist known for his work in mass spectrometry. He is best known for the McLafferty rearrangement reaction that was observed with mass spectrometry. With Roland Gohlke, he pioneered the technique of gas chromatography–mass spectrometry. He is also known for electron-capture dissociation, a method of fragmenting gas-phase ions.