François, Duke of Châtellerault

François de Bourbon, duc de Châtellerault (1492 – 13 September 1515) was a French prince du sang and soldier during the Italian Wars. The son of Gilbert de Bourbon, comte de Montpensier (count of Montpensier) and Clara Gonzaga, Châtellerault had two elder brothers, one of whom was the famous duc de Bourbon (duke of Bourbon).

At the advent of the reign of the French king François I, or Francis I, Châtellerault played a ceremonial role in the new king's coronation, standing in for the duc de Guyenne. François made Châtellerault into a duc, where previously he had been a vicomte (viscount). The duc de Châtellerault participated in the French 1515 campaign into Italy to reconquer territories for France as part of the vanguard of the army. This campaign culminated at the victorious battle of Marignano at which Châtellerault was killed. His titles went to his elder brother the duc de Bourbon.