Fifth disease

Erythema infectiosum
Other namesFifth disease, slapped cheek syndrome, slapcheek, slap face, slapped face
16-month-old with erythema infectiosum, displaying characteristic red rashes
SpecialtyInfectious disease
SymptomsRed rash, especially on cheeks and harsh coughs
CausesHuman parvovirus

Fifth disease, also known as erythema infectiosum and slapped cheek syndrome, is a common and contagious disease caused by infection with parvovirus B19. This virus was discovered in 1975 and can cause other diseases besides fifth disease. Fifth disease typically presents as a rash and is most common in children. Parvovirus B19 can affect people of all ages; about two out of ten persons infected will have no symptoms.

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