FRS3

FRS3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KUP, 2KUQ, 2YS5, 2YT2
Identifiers
Aliases	FRS3, FRS2-beta, FRS2B, FRS2beta, SNT-2, SNT2, fibroblast growth factor receptor substrate 3
External IDs	OMIM: 607744; MGI: 2135965; HomoloGene: 4845; GeneCards: FRS3; OMA:FRS3 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	41,786,542 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	48,015,211 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; anterior cingulate cortex; ; prefrontal cortex; ; right frontal lobe; ; Brodmann area 9; ; Hypothalamus; ; Amygdala; ; right testis; ; apex of heart; ; left testis;
	Top expressed in
	neural layer of retina; ; spermatocyte; ; central gray substance of midbrain; ; yolk sac; ; primary visual cortex; ; cerebellar cortex; ; superior frontal gyrus; ; nucleus of stria terminalis; ; paraventricular nucleus of hypothalamus; ; seminiferous tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; fibroblast growth factor receptor binding; identical protein binding;
Cellular component	plasma membrane; membrane; intracellular anatomical structure;
Biological process	fibroblast growth factor receptor signaling pathway; signal transduction; MAPK cascade;
	Sources:Amigo / QuickGO
Orthologs
	10817
	107971
	ENSG00000137218
	ENSMUSG00000023266
	O43559
	Q91WJ0
	NM_006653
	NM_144939
	NP_006644
	NP_659188
	Wikidata
View/Edit Human	View/Edit Mouse

Fibroblast growth factor receptor substrate 3 is a protein that in humans is encoded by the FRS3 gene.

The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras.