FOXI3

FOXI3
Identifiers
Aliases	FOXI3, forkhead box I3
External IDs	OMIM: 612351; MGI: 3511278; HomoloGene: 52949; GeneCards: FOXI3; OMA:FOXI3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	88,452,693 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	70,938,050 bp
RNA expression pattern
	Top expressed in
	gonad; ; placenta; ; testicle; ; ganglionic eminence; ; anterior pituitary; ; skin of abdomen; ; skin of leg; ; renal cortex;
	Top expressed in
	pharyngeal pouch; ; cervical loop; ; stellate reticulum; ; hair follicle; ; salivary gland; ; epiblast; ; inner enamel epithelium; ; surface ectoderm; ; embryo; ; lens;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	344167
	232077
	ENSG00000214336
	ENSMUSG00000055874
	A8MTJ6
	n/a
	NM_001135649
	NM_001101464
	NP_001129121
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Forkead box I3 (FOXI3) is a protein that in humans is encoded by the FOXI3 gene. FOXI3 is a forkhead box transcription factor that is expressed in the development of hair and teeth. One of its mutations is a dominant allele responsible for the heterozygous Hh hairless trait in dogs. It was identified in 2008.