FGFBP1

FGFBP1
Identifiers
Aliases	FGFBP1, FGF-BP, FGF-BP1, FGFBP, FGFBP-1, HBP17, fibroblast growth factor binding protein 1
External IDs	OMIM: 607737; MGI: 1096350; HomoloGene: 3766; GeneCards: FGFBP1; OMA:FGFBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	15,938,740 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	44,139,121 bp
RNA expression pattern
	Top expressed in
	mucosa of pharynx; ; gums; ; gingival epithelium; ; mucosa of esophagus; ; oral cavity; ; mucosa of transverse colon; ; human penis; ; vulva; ; skin of abdomen; ; skin of leg;
	Top expressed in
	corneal stroma; ; mucous cell of stomach; ; skin of abdomen; ; epithelium of stomach; ; optic nerve; ; esophagus; ; umbilical cord; ; lip; ; pyloric antrum; ; left colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	fibroblast growth factor binding; heparin binding; protein binding; growth factor binding;
Cellular component	extracellular region; cell surface; plasma membrane; membrane; extracellular space;
Biological process	positive regulation of fibroblast growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; signal transduction; positive regulation of cell population proliferation; negative regulation of cell population proliferation; cell-cell signaling; positive regulation of cell migration involved in sprouting angiogenesis; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis;
	Sources:Amigo / QuickGO
Orthologs
	9982
	14181
	ENSG00000137440
	ENSMUSG00000048373
	Q14512
	O70514
	NM_005130
	NM_001271616; NM_008009
	NP_005121
	NP_001258545; NP_032035
	Wikidata
View/Edit Human	View/Edit Mouse

Fibroblast growth factor-binding protein 1 is a protein that in humans is encoded by the FGFBP1 gene.

FGFBP1, or HBP17, binds to both acidic FGF1 and basic FGF2 fibroblast growth factors in a reversible manner. It also binds to perlecan (HSPG2).[supplied by OMIM]