FBP1

FBP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1FTA, 2FHY, 2FIE, 2FIX, 2JJK, 2VT5, 2WBB, 2WBD, 2Y5K, 2Y5L, 3A29, 3KBZ, 3KC0, 3KC1, 4MJO
Identifiers
Aliases	FBP1, FBP, fructose-bisphosphatase 1
External IDs	OMIM: 611570; MGI: 95492; HomoloGene: 55467; GeneCards: FBP1; OMA:FBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	94,640,249 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	63,036,096 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; jejunal mucosa; ; mucosa of ileum; ; duodenum; ; human kidney; ; right lung; ; upper lobe of left lung; ; kidney tubule; ; monocyte; ; mucosa of transverse colon;
	Top expressed in
	left lobe of liver; ; right kidney; ; human kidney; ; seminiferous tubule; ; gallbladder; ; spermatocyte; ; spermatid; ; proximal tubule; ; epithelium of small intestine; ; Ileal epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; metal ion binding; phosphoric ester hydrolase activity; identical protein binding; hydrolase activity; catalytic activity; monosaccharide binding; AMP binding; phosphatase activity; fructose 1,6-bisphosphate 1-phosphatase activity;
Cellular component	cytoplasm; extracellular exosome; cytosol; nucleus;
Biological process	fructose metabolic process; fructose 6-phosphate metabolic process; cellular response to magnesium ion; metabolism; dephosphorylation; regulation of gluconeogenesis; negative regulation of cell growth; protein homotetramerization; negative regulation of Ras protein signal transduction; gluconeogenesis; sucrose biosynthetic process; fructose 1,6-bisphosphate metabolic process; carbohydrate metabolic process; negative regulation of transcription by RNA polymerase II; negative regulation of glycolytic process;
	Sources:Amigo / QuickGO
Orthologs
	2203
	14121
	ENSG00000165140
	ENSMUSG00000069805
	P09467
	Q9QXD6
	NM_000507; NM_001127628
	NM_019395
	NP_000498; NP_001121100
	NP_062268
	Wikidata
View/Edit Human	View/Edit Mouse

Fructose-1,6-bisphosphatase 1 is a protein that in humans is encoded by the FBP1 gene.