FADS1

FADS1
Identifiers
Aliases	FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12, fatty acid desaturase 1
External IDs	OMIM: 606148; MGI: 1923517; HomoloGene: 22753; GeneCards: FADS1; OMA:FADS1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	61,829,318 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	10,174,241 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; ventral tegmental area; ; superior vestibular nucleus; ; ventricular zone; ; spinal ganglia; ; internal globus pallidus; ; ganglionic eminence; ; trigeminal ganglion; ; inferior ganglion of vagus nerve; ; subthalamic nucleus;
	Top expressed in
	adrenal gland; ; tail of embryo; ; genital tubercle; ; choroid plexus of fourth ventricle; ; Epithelium of choroid plexus; ; left lobe of liver; ; sciatic nerve; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; vestibular membrane of cochlear duct;
	More reference expression data
	n/a
Gene ontology
Molecular function	C-5 sterol desaturase activity; oxidoreductase activity; omega-6 fatty acid desaturase activity; acyl-CoA delta5-desaturase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; mitochondrion; endoplasmic reticulum;
Biological process	linoleic acid metabolic process; regulation of transcription, DNA-templated; lipid metabolism; cellular response to starvation; cell-cell signaling; alpha-linolenic acid metabolic process; fatty acid metabolic process; icosanoid biosynthetic process; fatty acid biosynthetic process; phospholipid biosynthetic process; unsaturated fatty acid biosynthetic process; regulation of cell differentiation; regulation of lipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	3992
	76267
	ENSG00000149485
	ENSMUSG00000010663
	O60427
	Q920L1
	NM_013402
	NM_146094
	NP_037534
	NP_666206
	Wikidata
View/Edit Human	View/Edit Mouse

Fatty acid desaturase 1 (FADS1) is an enzyme that in humans is encoded by the FADS1 gene.