Einhorn–Brunner reaction

The Einhorn–Brunner reaction is the designation for the chemical reaction of imides with alkyl hydrazines to form an isomeric mixture of 1,2,4-triazoles. It was initially described by the German chemist Alfred Einhorn in a paper, published in 1905, describing N-methylol compounds of amides. In 1914 chemist Karl Brunner published a paper expanding on Einhorn's research of the reaction pictured below, thus resulting in the naming as the Einhorn-Brunner. Substituted 1,2,4-triazole have been prepared from diverse imides and hydrazines.