DUSP6

DUSP6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1HZM, 1MKP
Identifiers
Aliases	DUSP6, HH19, MKP3, PYST1, dual specificity phosphatase 6
External IDs	OMIM: 602748; MGI: 1914853; HomoloGene: 55621; GeneCards: DUSP6; OMA:DUSP6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	89,352,501 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	99,103,351 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; pericardium; ; monocyte; ; lactiferous duct; ; visceral pleura; ; lower lobe of lung; ; retinal pigment epithelium; ; granulocyte; ; parietal pleura; ; trachea;
	Top expressed in
	granulocyte; ; left lung lobe; ; stroma of bone marrow; ; maxillary prominence; ; retinal pigment epithelium; ; parotid gland; ; endocardial cushion; ; tail of embryo; ; atrioventricular valve; ; right lung lobe;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	phosphoprotein phosphatase activity; phosphatase activity; hydrolase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity;
Cellular component	nucleoplasm; cytosol; cytoplasm;
Biological process	negative regulation of protein phosphorylation; cell differentiation; positive regulation of cell death; response to organic cyclic compound; regulation of fibroblast growth factor receptor signaling pathway; protein dephosphorylation; response to organic substance; MAPK cascade; response to nitrosative stress; positive regulation of apoptotic process; negative regulation of ERK1 and ERK2 cascade; peptidyl-tyrosine dephosphorylation; response to growth factor; dorsal/ventral pattern formation; regulation of endodermal cell fate specification; dephosphorylation; regulation of heart growth;
	Sources:Amigo / QuickGO
Orthologs
	1848
	67603
	ENSG00000139318
	ENSMUSG00000019960
	Q16828
	Q9DBB1
	NM_022652; NM_001946
	NM_026268
	NP_001937; NP_073143
	NP_080544
	Wikidata
View/Edit Human	View/Edit Mouse

Dual specificity phosphatase 6 (DUSP6) is an enzyme that in humans is encoded by the DUSP6 gene.