DLGAP1

DLGAP1
Identifiers
Aliases	DLGAP1, DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, DLGAP1A, DLGAP1B, GKAP, SAPAP1, hGKAP, discs large homolog associated protein 1, DLG associated protein 1
External IDs	OMIM: 605445; MGI: 1346065; HomoloGene: 31258; GeneCards: DLGAP1; OMA:DLGAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	4,455,307 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	71,128,408 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; endothelial cell; ; primary visual cortex; ; prefrontal cortex; ; Pons; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; parietal lobe; ; superior frontal gyrus; ; right frontal lobe;
	Top expressed in
	piriform cortex; ; subiculum; ; primary motor cortex; ; cingulate gyrus; ; subdivision of hippocampus; ; Region I of hippocampus proper; ; lateral septal nucleus; ; cerebellar vermis; ; lobe of cerebellum; ; anterior amygdaloid area;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein domain specific binding; protein-containing complex binding;
Cellular component	cell junction; postsynaptic membrane; postsynaptic density; membrane; plasma membrane; synapse; cellular component;
Biological process	signaling; chemical synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	9229
	224997
	ENSG00000170579
	ENSMUSG00000003279
	O14490
	Q9D415
NM_001003809; NM_001242761; NM_001242762; NM_001242763; NM_001242764;
	NM_001242765; NM_001242766; NM_001308390; NM_004746
NM_001128180; NM_001128181; NM_027712; NM_177639; NM_001347411;
	NM_001347412; NM_001347413; NM_001347414; NM_001360665
NP_001003809; NP_001229690; NP_001229691; NP_001229692; NP_001229693;
	NP_001229694; NP_001229695; NP_001295319; NP_004737
NP_001121652; NP_001121653; NP_001334340; NP_001334341; NP_001334342;
	NP_001334343; NP_081988; NP_808307; NP_001347594
	Wikidata
View/Edit Human	View/Edit Mouse

Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP), is a protein that in humans is encoded by the DLGAP1 gene. DAP-1 is known to be highly enriched in synaptosomal preparations of the brain, and present in the post-synaptic density.