DDX21

DDX21
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2M3D
Identifiers
Aliases	DDX21, GUA, GURDB, RH-II/GU, RH-II/GuA, DEAD-box helicase 21, DExD-box helicase 21
External IDs	OMIM: 606357; MGI: 1860494; HomoloGene: 3473; GeneCards: DDX21; OMA:DDX21 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	68,985,068 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	62,438,060 bp
RNA expression pattern
	Top expressed in
	pericardium; ; cartilage tissue; ; mucosa of urinary bladder; ; mucosa of pharynx; ; gingival epithelium; ; vena cava; ; lower lobe of lung; ; nipple; ; lactiferous duct; ; human penis;
	Top expressed in
	epiblast; ; cumulus cell; ; somite; ; primitive streak; ; tail of embryo; ; hair follicle; ; mandibular prominence; ; maxillary prominence; ; abdominal wall; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; rRNA binding; helicase activity; 7SK snRNA binding; protein binding; nucleic acid binding; double-stranded RNA binding; hydrolase activity; ATP binding; snoRNA binding; RNA binding; miRNA binding; identical protein binding;
Cellular component	membrane; nucleoplasm; nucleus; nucleolus; cytoplasm; mitochondrion; cytosol;
Biological process	epigenetic maintenance of chromatin in transcription-competent conformation; response to exogenous dsRNA; response to virus; transcription by RNA polymerase II; transcription, DNA-templated; osteoblast differentiation; RNA secondary structure unwinding; rRNA processing; immune system process; positive regulation of myeloid dendritic cell cytokine production; positive regulation of I-kappaB kinase/NF-kappaB signaling; innate immune response; defense response to virus;
	Sources:Amigo / QuickGO
Orthologs
	9188
	56200
	ENSG00000165732
	ENSMUSG00000020075
	Q9NR30
	Q9JIK5
	NM_001256910; NM_004728
	NM_019553
	NP_001243839; NP_004719
	NP_062426
	Wikidata
View/Edit Human	View/Edit Mouse

Nucleolar RNA helicase 2 is an enzyme that in humans is encoded by the DDX21 gene.