Combretastatin A-4

Combretastatin A-4
Names
	Preferred IUPAC name 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethen-1-yl]phenol
	Other names Combretastatin A4; CA-4; 1-(3,4,5-Trimethoxyphenyl)-2-(3′-hydroxy-4′-methoxyphenyl)ethene; 3,4,5-Trimethoxy-3′-hydroxy-4′-methoxystilbene
Identifiers
CAS Number	117048-59-6 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL67 ;
ChemSpider	4508364 ;
ECHA InfoCard	100.159.667
PubChem CID	5351344;
UNII	16U6OP69RQ ;
CompTox Dashboard (EPA)	DTXSID101025983 ;
	InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5- Key: HVXBOLULGPECHP-WAYWQWQTSA-N ;
	SMILES COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)O;
Properties
Chemical formula	C18H20O5
Molar mass	316.34 g/mol
Melting point	116 °C (241 °F; 389 K)
Solubility in water	insoluble
Solubility in DMSO, Ethanol	DMSO : 63 mg/mL, Ethanol : 34 mg/mL
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Combretastatin A-4 is a combretastatin and a stilbenoid. It can be isolated from Combretum afrum, the Eastern Cape South African bushwillow tree or in Combretum leprosum, the mofumbo, a species found in Brazil.

Names

Preferred IUPAC name 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethen-1-yl]phenol
Other names Combretastatin A4 CA-4 1-(3,4,5-Trimethoxyphenyl)-2-(3′-hydroxy-4′-methoxyphenyl)ethene 3,4,5-Trimethoxy-3′-hydroxy-4′-methoxystilbene
Identifiers
CAS Number	117048-59-6^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL67^Y
ChemSpider	4508364^Y
ECHA InfoCard	100.159.667
PubChem CID	5351344
UNII	16U6OP69RQ^Y
CompTox Dashboard (EPA)	DTXSID101025983
InChI InChI=1S/C18H20O5/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11,19H,1-4H3/b6-5-^Y Key: HVXBOLULGPECHP-WAYWQWQTSA-N^Y
SMILES COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)O
Properties
Chemical formula	C₁₈H₂₀O₅
Molar mass	316.34 g/mol
Melting point	116 °C (241 °F; 389 K)
Solubility in water	insoluble
Solubility in DMSO, Ethanol	DMSO : 63 mg/mL, Ethanol : 34 mg/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references