Clenbuterol

Clenbuterol
	Clenbuterol (top),; and (R)-(−)-clenbuterol (bottom)
Clinical data
Trade names	Dilaterol, Spiropent, Ventipulmin, others
AHFS/Drugs.com	International Drug Names
Pregnancy; category	C;
Routes of; administration	By mouth
Drug class	β2-adrenergic receptor agonist
ATC code	R03AC14 (WHO) R03CC13 (WHO) QG02CA91 (WHO);
Legal status
Legal status	AU: S4 (Prescription only); UK: POM (Prescription only); US: ℞-only;
Pharmacokinetic data
Bioavailability	89–98% (orally)
Metabolism	Hepatic (negligible)
Elimination half-life	36–48 hours
Excretion	Feces and urine
Identifiers
	IUPAC name (RS)-1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethan-1-ol;
CAS Number	37148-27-9 ;
PubChem CID	2783;
IUPHAR/BPS	12582;
DrugBank	DB01407 ;
ChemSpider	2681 ;
UNII	XTZ6AXU7KN;
KEGG	D07713 ;
ChEBI	CHEBI:174690 ;
ChEMBL	ChEMBL49080 ;
CompTox Dashboard (EPA)	DTXSID7022833 ;
ECHA InfoCard	100.048.499
Chemical and physical data
Formula	C12H18Cl2N2O
Molar mass	277.19 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES Clc1cc(cc(Cl)c1N)C(O)CNC(C)(C)C;
	InChI InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3 ; Key:STJMRWALKKWQGH-UHFFFAOYSA-N ;
	(verify)

Clenbuterol is a sympathomimetic amine used by sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this as a bronchodilator to make breathing easier. It is most commonly available as the hydrochloride salt, clenbuterol hydrochloride.

It was patented in 1967 and came into medical use in 1977.

Clinical data

Clenbuterol (top), and (R)-(−)-clenbuterol (bottom)
Trade names	Dilaterol, Spiropent, Ventipulmin, others
AHFS/Drugs.com	International Drug Names
Pregnancy category	C
Routes of administration	By mouth
Drug class	β₂-adrenergic receptor agonist
ATC code	R03AC14 (WHO) R03CC13 (WHO) QG02CA91 (WHO)
Legal status
Legal status	AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability	89–98% (orally)
Metabolism	Hepatic (negligible)
Elimination half-life	36–48 hours
Excretion	Feces and urine
Identifiers
IUPAC name (RS)-1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethan-1-ol
CAS Number	37148-27-9^Y
PubChem CID	2783
IUPHAR/BPS	12582
DrugBank	DB01407^Y
ChemSpider	2681^Y
UNII	XTZ6AXU7KN
KEGG	D07713^Y
ChEBI	CHEBI:174690^Y
ChEMBL	ChEMBL49080^Y
CompTox Dashboard (EPA)	DTXSID7022833
ECHA InfoCard	100.048.499
Chemical and physical data
Formula	C₁₂H₁₈Cl₂N₂O
Molar mass	277.19 g·mol⁻¹
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES Clc1cc(cc(Cl)c1N)C(O)CNC(C)(C)C
InChI InChI=1S/C12H18Cl2N2O/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7/h4-5,10,16-17H,6,15H2,1-3H3^Y Key:STJMRWALKKWQGH-UHFFFAOYSA-N^Y
(verify)