Cacodylic acid
| Names | |
|---|---|
| Preferred IUPAC name
Dimethylarsinic acid | |
| Other names
Dimethylarsenic acid, Cacodylic acid, Hydroxydimethylarsine oxide, Arsecodile, Ansar, Silvisar, Phytar 560, DMAA, UN 1572 | |
| Identifiers | |
3D model (JSmol) |
|
| 1736965 | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.000.804 |
| EC Number |
|
| 130562 | |
| KEGG | |
PubChem CID |
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| RTECS number |
|
| UNII | |
| UN number | 1572 |
CompTox Dashboard (EPA) |
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| |
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| Properties | |
| C2H7AsO2 | |
| Molar mass | 137.9977 g/mol |
| Appearance | White crystals or powder |
| Odor | odorless |
| Density | > 1.1 g/cm3 |
| Melting point | 192 to 198 °C (378 to 388 °F; 465 to 471 K) |
| Boiling point | > 200 °C (392 °F; 473 K) |
| 66.7 g/100 ml | |
| Solubility | soluble in ethanol, acetic acid insoluble in diethyl ether |
| Acidity (pKa) | 6 |
| −79.9·10−6 cm3/mol | |
| Structure | |
| triclinic, monoclinic | |
| Hazards | |
| GHS labelling: | |
| Danger | |
| H301, H331, H410 | |
| P261, P264, P270, P271, P273, P301+P310, P304+P340, P311, P321, P330, P391, P403+P233, P405, P501 | |
| NFPA 704 (fire diamond) | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
23-100 mg/kg (rat and mouse, oral) |
| Safety data sheet (SDS) | External MSDS |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
Cacodylic acid is an organoarsenic compound with the formula (CH3)2AsO2H. With the formula R2As(O)OH, it is the simplest of the arsinic acids. It is a colorless solid that is soluble in water.
Neutralization of cacodylic acid with base gives cacodylate salts, e.g. sodium cacodylate. They are potent herbicides. Cacodylic acid/sodium cacodylate is a buffering agent in the preparation and fixation of biological samples for electron microscopy and in protein crystallography.