CSRP3

CSRP3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2O10, 2O13
Identifiers
Aliases	CSRP3, CLP, CMD1M, CMH12, CRP3, LMO4, MLP, cysteine and glycine rich protein 3
External IDs	OMIM: 600824; MGI: 1330824; HomoloGene: 20742; GeneCards: CSRP3; OMA:CSRP3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	19,210,571 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	48,497,781 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; right ventricle; ; myocardium of left ventricle; ; apex of heart; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; thoracic diaphragm; ; glutes; ; cardiac muscle tissue of right atrium; ; right auricle of heart;
	Top expressed in
	atrioventricular valve; ; endocardial cushion; ; interventricular septum; ; right ventricle; ; cardiac muscles; ; myocardium of ventricle; ; ankle; ; atrium; ; esophagus; ; soleus muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actinin binding; metal ion binding; telethonin binding; protein binding; structural constituent of muscle; actin binding; identical protein binding;
Cellular component	cytoplasm; Z discdkac; cytoskeleton; nucleus; sarcomere;
Biological process	protein localization to organelle; cell differentiation; negative regulation of myoblast differentiation; cardiac muscle contraction; cardiac muscle tissue development; regulation of the force of heart contraction; cardiac muscle hypertrophy; muscle organ development; cellular calcium ion homeostasis; positive regulation of actin filament severing; detection of muscle stretch; cardiac myofibril assembly; multicellular organism development; positive regulation of myoblast differentiation; negative regulation of actin filament severing; skeletal muscle tissue development; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated; regulation of transcription, DNA-templated; inflammatory response; heart development; insulin receptor signaling pathway; T-tubule organization; glucose homeostasis; protein kinase C signaling; regulation of protein localization to plasma membrane; actin cytoskeleton organization; sarcomere organization; muscle tissue development;
	Sources:Amigo / QuickGO
Orthologs
	8048
	13009
	ENSG00000129170
	ENSMUSG00000030470
	P50461
	P50462
	NM_003476; NM_001369404
	NM_001198841; NM_013808
	NP_003467
	NP_001185770; NP_038836
	Wikidata
View/Edit Human	View/Edit Mouse

Cysteine and glycine-rich protein 3 also known as cardiac LIM protein (CLP) or muscle LIM protein (MLP) is a protein that in humans is encoded by the CSRP3 gene.

CSRP3 IS a small 194 amino acid protein, which is specifically expressed in skeletal and cardiac muscle. In rodents, CSRP3 has also been found to be expressed in neurons.