CLCN7

CLCN7
Identifiers
Aliases	CLCN7, CLC-7, CLC7, OPTA2, OPTB4, PPP1R63, chloride voltage-gated channel 7, HOD
External IDs	OMIM: 602727; MGI: 1347048; HomoloGene: 56546; GeneCards: CLCN7; OMA:CLCN7 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	1,475,084 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	25,381,078 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal cortex; ; right hemisphere of cerebellum; ; stromal cell of endometrium; ; granulocyte; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; spleen; ; anterior pituitary; ; right frontal lobe;
	Top expressed in
	superior surface of tongue; ; gallbladder; ; ganglion of vagus nerve; ; stroma of bone marrow; ; neural layer of retina; ; right kidney; ; decidua; ; entorhinal cortex; ; perirhinal cortex; ; ankle joint;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ion channel activity; antiporter activity; ATP binding; chloride channel activity; voltage-gated chloride channel activity; protein binding; chloride transmembrane transporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; lysosome; cytoplasmic vesicle; lysosomal membrane; membrane; nucleoplasm; intracellular membrane-bounded organelle;
Biological process	ion transmembrane transport; chloride transport; ion transport; regulation of anion transmembrane transport; response to pH; transmembrane transport; chloride transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	1186
	26373
	ENSG00000103249
	ENSMUSG00000036636
	P51798
	O70496
	NM_001114331; NM_001287
	NM_011930; NM_001317404
	NP_001107803; NP_001278
	NP_001304333; NP_036060
	Wikidata
View/Edit Human	View/Edit Mouse

Chloride channel 7 alpha subunit also known as H⁺/Cl⁻ exchange transporter 7 is a protein that in humans is encoded by the CLCN7 gene. In melanocytic cells this gene is regulated by the Microphthalmia-associated transcription factor.