CHST6

CHST6
Identifiers
Aliases	CHST6, MCDC1, carbohydrate sulfotransferase 6, GST4-beta, gn6st-5, hCGn6ST, glcNAc6ST-5, C-GlcNAc6ST
External IDs	OMIM: 605294; MGI: 1931825; HomoloGene: 56927; GeneCards: CHST6; OMA:CHST6 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	75,495,445 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	112,637,079 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; nasal epithelium; ; tibia; ; mucosa of paranasal sinus; ; olfactory zone of nasal mucosa; ; trachea; ; external globus pallidus; ; inferior ganglion of vagus nerve; ; subthalamic nucleus; ; pars reticulata;
	Top expressed in
	vestibular sensory epithelium; ; utricle; ; trachea; ; cornea; ; iris; ; vestibular membrane of cochlear duct; ; trigeminal ganglion; ; lumbar spinal ganglion; ; stria vascularis; ; superior cervical ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	sulfotransferase activity; transferase activity; N-acetylglucosamine 6-O-sulfotransferase activity;
Cellular component	Golgi apparatus; Golgi membrane; membrane; integral component of membrane; trans-Golgi network;
Biological process	sulfur compound metabolic process; keratan sulfate biosynthetic process; N-acetylglucosamine metabolic process; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	4166
	56773
	ENSG00000183196
	ENSMUSG00000031952
	Q9GZX3
	Q9QUP4
	NM_021615
	NM_019950
	NP_067628
	NP_064334
	Wikidata
View/Edit Human	View/Edit Mouse

Carbohydrate sulfotransferase 6 is an enzyme that in humans is encoded by the CHST6 gene.

It codes for an enzyme necessary for the production of keratan sulfate. Mutations in the gene lead to macular corneal dystrophy.