CEP70

CEP70
Identifiers
Aliases	CEP70, BITE, centrosomal protein 70
External IDs	OMIM: 614310; MGI: 1915371; HomoloGene: 11387; GeneCards: CEP70; OMA:CEP70 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	138,594,538 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	99,300,404 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; sperm; ; right uterine tube; ; ventricular zone; ; left testis; ; right testis; ; ganglionic eminence; ; body of pancreas; ; duodenum; ; jejunal mucosa;
	Top expressed in
	zygote; ; secondary oocyte; ; spermatocyte; ; genital tubercle; ; primary oocyte; ; trigeminal ganglion; ; substantia nigra; ; saccule; ; ventricular zone; ; ganglionic eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding; gamma-tubulin binding;
Cellular component	microtubule organizing center; cytoskeleton; cytoplasm; nucleoplasm; cytosol; nuclear membrane; centrosome;
Biological process	G2/M transition of mitotic cell cycle; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle; cilium assembly; regulation of microtubule cytoskeleton organization;
	Sources:Amigo / QuickGO
Orthologs
	80321
	68121
	ENSG00000114107
	ENSMUSG00000056267
	Q8NHQ1
	Q6IQY5
NM_001288964; NM_001288965; NM_001288966; NM_001288967; NM_024491;
	NM_001320598; NM_001320599; NM_001320600
	NM_023873
NP_001275893; NP_001275894; NP_001275895; NP_001275896; NP_001307527;
	NP_001307528; NP_001307529; NP_077817
	NP_076362
	Wikidata
View/Edit Human	View/Edit Mouse

Centrosomal protein of 70 kDa is a protein that in humans is encoded by the CEP70 gene. The protein interacts with γ-tubulin through its coiled coil domains to localize at the centrosome. CEP70 is involved in organizing microtubules in interphase cells and is required for proper organization and orientation of the mitotic spindle.