CD164

CD164
Identifiers
Aliases	CD164, MGC-24, MUC-24, endolyn, DFNA66, CD164 molecule, MGC-24v
External IDs	OMIM: 603356; MGI: 1859568; HomoloGene: 38129; GeneCards: CD164; OMA:CD164 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	109,382,467 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	41,407,044 bp
RNA expression pattern
	Top expressed in
	mucosa of sigmoid colon; ; bronchial epithelial cell; ; kidney tubule; ; secondary oocyte; ; skin of hip; ; lactiferous duct; ; rectum; ; epithelium of nasopharynx; ; glomerulus; ; skin of thigh;
	Top expressed in
	parotid gland; ; submandibular gland; ; epithelium of lens; ; Epithelium of choroid plexus; ; iris; ; retinal pigment epithelium; ; lacrimal gland; ; vestibular membrane of cochlear duct; ; cornea; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; extracellular region; lysosomal membrane; endosome; plasma membrane; lysosome; integral component of plasma membrane; endosome membrane; membrane; cytoplasmic vesicle;
Biological process	multicellular organism development; negative regulation of cell adhesion; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; cell adhesion; muscle organ development; immune response; signal transduction; negative regulation of cell population proliferation; hemopoiesis;
	Sources:Amigo / QuickGO
Orthologs
	8763
	53599
	ENSG00000135535
	ENSMUSG00000019818
	Q04900
	Q9R0L9
NM_006016; NM_001142401; NM_001142402; NM_001142403; NM_001142404;
	NM_001346500
	NM_016898
NP_001135873; NP_001135874; NP_001135875; NP_001135876; NP_001333429;
	NP_006007
	NP_058594
	Wikidata
View/Edit Human	View/Edit Mouse

Sialomucin core protein 24 also known as endolyn or CD164 (cluster of differentiation 164) is a protein that in humans is encoded by the CD164 gene. CD164 functions as a cell adhesion molecule.

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play two key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor.