CCNC (gene)

CCNC
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3RGF, 4F6S, 4F6U, 4F6W, 4F70, 4F7J, 4F7L, 4F7N, 4F7S, 4G6L, 4CRL, 5HBE, 5HBH, 5BNJ, 5HBJ, 5FGK, 5CEI, 5HNB, 5HVY, 5I5Z
Identifiers
Aliases	CCNC, CycC, cyclin C, hSRB11, SRB11
External IDs	OMIM: 123838; MGI: 1858199; HomoloGene: 3803; GeneCards: CCNC; OMA:CCNC - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	99,568,825 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	21,759,922 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; oral cavity; ; corpus epididymis; ; jejunal mucosa; ; islet of Langerhans; ; nasal epithelium; ; mucosa of sigmoid colon; ; skin of thigh; ; caput epididymis; ; amniotic fluid;
	Top expressed in
	spermatid; ; spermatocyte; ; ventricular zone; ; right kidney; ; embryo; ; pineal gland; ; ventral tegmental area; ; medial vestibular nucleus; ; genital tubercle; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein serine/threonine kinase activity; cyclin-dependent protein serine/threonine kinase regulator activity;
Cellular component	mediator complex; cyclin-dependent protein kinase holoenzyme complex; nucleus; nucleoplasm;
Biological process	positive regulation of phosphorylation of RNA polymerase II C-terminal domain; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-templated; positive regulation of cyclin-dependent protein serine/threonine kinase activity; positive regulation of transcription by RNA polymerase II; protein phosphorylation; transcription, DNA-templated; regulation of cyclin-dependent protein serine/threonine kinase activity; regulation of transcription by RNA polymerase II; regulation of protein kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	892
	51813
	ENSG00000112237
	ENSMUSG00000028252
	P24863
	Q62447
	NM_001013399; NM_005190; NM_001363537
	NM_001122982; NM_001290420; NM_001290422; NM_016746
	NP_001013417; NP_005181; NP_001350466
	NP_001116454; NP_001277349; NP_001277351; NP_058026
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclin-C is a protein that in humans is encoded by the CCNC gene.

The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phosphorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.