Generalized bullous fixed drug eruption
| Generalized bullous fixed drug eruption | |
|---|---|
| Other names | Bullous drug eruption, multilocular bullous fixed drug eruption: 554 |
| Drug eruption: Bullous dermatitis medicamentosa caused by sulfathiazole. | |
| Specialty | Dermatology |
Generalized bullous fixed drug eruption (GBFDE) most commonly refers to a drug reaction in the erythema multiforme group.: 129 These are uncommon reactions to medications, with an incidence of 0.4 to 1.2 per million person-years for toxic epidermal necrolysis and 1.2 to 6.0 per million person-years for Stevens–Johnson syndrome.: 129 The primary skin lesions are large erythemas (faintly discernible even after confluence), most often irregularly distributed and of a characteristic purplish-livid color, at times with flaccid blisters.: 554