Brian David Dynlacht

Brian David Dynlacht (born September 3, 1965), is an American biochemist and professor in the department of pathology of New York University Grossman School of Medicine at NYU Langone Health. Before moving his lab to New York University, he was an associate professor in the department of molecular and cellular biology at Harvard University. In 2002, while researching at the Harvard University, Dynlacht reported the discovery of CP110, which is now thought to be at the center of a molecular switch governing the centriole to ciliary transition in mammalian cells. His lab identified the first centriolar deubiquitinating enzyme, USP33, whose expression regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110, and thus regulates the centrosome duplication.