Transcription factor IIIB 50 kDa subunit

BRF2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4ROD, 4ROE, 4ROC
Identifiers
Aliases	BRF2, BRFU, TFIIIB50, RNA polymerase III transcription initiation factor 50 kDa subunit, RNA polymerase III transcription initiation factor subunit, BRF2 RNA polymerase III transcription initiation factor subunit
External IDs	OMIM: 607013; MGI: 1913903; HomoloGene: 10127; GeneCards: BRF2; OMA:BRF2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	37,849,861 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	27,618,708 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; tibialis anterior muscle; ; deltoid muscle; ; Skeletal muscle tissue of biceps brachii; ; gastrocnemius muscle; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; decidua; ; beta cell; ; muscle of thigh;
	Top expressed in
	primary oocyte; ; spermatid; ; spermatocyte; ; zygote; ; secondary oocyte; ; interventricular septum; ; seminiferous tubule; ; morula; ; hand; ; superior cervical ganglion;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; RNA polymerase III type 3 promoter sequence-specific DNA binding; transcription factor binding;
Cellular component	nucleus; nucleoplasm; transcription factor TFIIIB complex;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase III; cellular response to oxidative stress; transcription preinitiation complex assembly; DNA-templated transcription, initiation; RNA polymerase III preinitiation complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	55290
	66653
	ENSG00000104221
	ENSMUSG00000031487
	Q9HAW0
	Q3UAW9
	NM_018310
	NM_025686
	NP_060780
	NP_079962
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor IIIB 50 kDa subunit (TFIIIB50) also known as b-related factor 2 (BRF-2) is a protein that in humans is encoded by the BRF2 gene.