Atosiban

Atosiban
Clinical data
Trade names	Tractocile, Antocin, others
AHFS/Drugs.com	UK Drug Information
License data	EU EMA: by INN;
Routes of; administration	Intravenous
ATC code	G02CX01 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only); UK: POM (Prescription only); EU: Rx-only; In general: ℞ (Prescription only);
Identifiers
	IUPAC name 1-(3-Mercaptopropanoic acid)-; 2-(O-ethyl-D-tyrosine)-4-L-threonine-; 8-L-ornithine-oxytocin;
CAS Number	90779-69-4 ;
PubChem CID	5311010;
IUPHAR/BPS	2213;
DrugBank	DB09059;
ChemSpider	4470550 ;
UNII	081D12SI0Z;
KEGG	D03008 ;
ChEMBL	ChEMBL378642 ;
CompTox Dashboard (EPA)	DTXSID8048991 ;
ECHA InfoCard	100.234.128
Chemical and physical data
Formula	C43H67N11O12S2
Molar mass	994.19 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N)CNC(=O)[C@@H](NC(=O)[C@H]3N(C(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CCSSC1)Cc2ccc(OCC)cc2)[C@@H](C)CC)[C@H](O)C)CC(=O)N)CCC3)CCCN;
	InChI InChI=1S/C43H67N11O12S2/c1-5-23(3)35-41(63)53-36(24(4)55)42(64)50-29(20-32(45)56)38(60)51-30(43(65)54-17-8-10-31(54)40(62)49-27(9-7-16-44)37(59)47-21-33(46)57)22-68-67-18-15-34(58)48-28(39(61)52-35)19-25-11-13-26(14-12-25)66-6-2/h11-14,23-24,27-31,35-36,55H,5-10,15-22,44H2,1-4H3,(H2,45,56)(H2,46,57)(H,47,59)(H,48,58)(H,49,62)(H,50,64)(H,51,60)(H,52,61)(H,53,63)/t23-,24+,27-,28+,29-,30-,31-,35-,36-/m0/s1 ; Key:VWXRQYYUEIYXCZ-OBIMUBPZSA-N ;
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Atosiban, sold under the brand name Tractocile among others, is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. It was developed by Ferring Pharmaceuticals in Sweden and first reported in the literature in 1985. Originally marketed by Ferring Pharmaceuticals, it is licensed in proprietary and generic forms for the delay of imminent preterm birth in pregnant adult women.

The most commonly reported side effect is nausea.