Aristolochic acid

Aristolochic acid I
Names
	Preferred IUPAC name 8-Methoxy-6-nitro-2H-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
	Other names Aristinic acid; Aristolochia yellow; Aristolochic acid A; Aristolochin;Aristolochine; Descresept; Tardolyt;TR 1736
Identifiers
CAS Number	313-67-7 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL93353 ;
ChemSpider	2149 ;
KEGG	C08469 ;
PubChem CID	2236;
UNII	94218WFP5T ;
	InChI InChI=1S/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20) Key: BBFQZRXNYIEMAW-UHFFFAOYSA-N ; InChI=1/C17H11NO7/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13/h2-6H,7H2,1H3,(H,19,20) Key: BBFQZRXNYIEMAW-UHFFFAOYAG;
	SMILES [O-][N+](=O)c1cc4c(c2c1c(C(=O)O)cc3OCOc23)cccc4OC;
Properties
Chemical formula	C17H11NO7
Molar mass	341.275 g·mol−1
Appearance	yellow powder
Melting point	260 to 265 °C (500 to 509 °F; 533 to 538 K)
Solubility	Slightly soluble in most solvents.
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	carcinogenic
NFPA 704 (fire diamond)	2 1 0
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Aristolochic acids (English: /əˌrɪstəˈloʊkɪk/) are a family of carcinogenic, mutagenic, and nephrotoxic phytochemicals commonly found in the flowering plant family Aristolochiaceae (birthworts). Aristolochic acid (AA) I is the most abundant one. The family Aristolochiaceae includes the genera Aristolochia (birthwort) and Asarum (wild ginger), which are both commonly used in Chinese herbal medicine. Despite the host plants having a long history of use in traditional medicine, modern clinical research suggests aristolochic acids cause kidney and liver cancer. The FDA has issued warnings regarding consumption of AA-containing supplements.