Technetium (99mTc) arcitumomab
| Monoclonal antibody | |
|---|---|
| Type | Fab' fragment |
| Source | Mouse |
| Target | CEA |
| Clinical data | |
| Routes of administration | Intravenous |
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| Pharmacokinetic data | |
| Bioavailability | N/A |
| Elimination half-life | 13 ± 4 hours |
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| Chemical and physical data | |
| Molar mass | 54 kDa |
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Technetium (99mTc) arcitumomab was a drug used for the diagnostic imaging of colorectal cancers, marketed by Immunomedics. It consisted of the Fab' fragment of a monoclonal antibody (arcitumomab, trade name CEA-Scan) and a radionuclide, technetium-99m.
CEA-Scan was approved by the European Medicine Association (EMA) on October of 1996 for imaging in the case of metastases and/or recurrence in patients that were suffering from colon or rectum cancer. Under the same decision, it was also approved to be used in patients that were suspected to have colon or rectal carcinoma recurrence and/or metastasis in association with rising blood CEA-levels.