Ampyrone
| Names | |
|---|---|
| Preferred IUPAC name
4-Amino-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one | |
| Other names
solvapyrin A, aminoazophene, aminoantipyrene, aminoantipyrine, metapyrazone | |
| Identifiers | |
3D model (JSmol) |
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.001.321 |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C11H13N3O1 | |
| Molar mass | 203.24 g/mol |
| Density | 1.207g/cm3 |
| Melting point | 106 to 110 °C (223 to 230 °F; 379 to 383 K) |
| Boiling point | 309 °C (588 °F; 582 K) @760mmHg |
| Hazards | |
| Flash point | 140.7 °C (285.3 °F; 413.8 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. While the parent drug, aminopyrine, has been discouraged due to the risk of agranulocytosis, ampyrone itself has significantly lower toxicity. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates liver microsomes and is also used to measure extracellular water.