Agmatine
| Names | |
|---|---|
| IUPAC name
1-(4-Aminobutyl)guanidine | |
| Identifiers | |
3D model (JSmol) |
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.005.626 |
| EC Number |
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| KEGG | |
| MeSH | Agmatine |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C5H14N4 | |
| Molar mass | 130.195 g·mol−1 |
| Density | 1.2 g/ml |
| Melting point | 102 °C (216 °F; 375 K) |
| Boiling point | 281 °C (538 °F; 554 K) |
| high | |
| log P | −1.423 |
| Basicity (pKb) | 0.52 |
| Hazards | |
| Flash point | 95.8 °C (204.4 °F; 368.9 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
Agmatine, also known as 4-aminobutyl-guanidine, was discovered in 1910 by Albrecht Kossel. It is a chemical substance which is naturally created from the amino acid arginine. Agmatine has been shown to exert modulatory action at multiple molecular targets, notably: neurotransmitter systems, ion channels, nitric oxide (NO) synthesis, and polyamine metabolism and this provides bases for further research into potential pharmacological applications.