Acute myelomonocytic leukemia

Acute myelomonocytic leukemia
SpecialtyHematology, oncology

Acute myelomonocytic leukemia (AMML) is a form of acute myeloid leukemia that involves a proliferation of CFU-GM myeloblasts and monoblasts. AMML occurs with a rapid increase amount in white blood cell count and is defined by more than 20% of myeloblast in the bone marrow. It is classified under "M4" in the French-American-British classification (FAB). It is classified under "AML, not otherwise classified" in the WHO classification.

Translocations have been observed. Progression from myelodysplastic syndrome has been reported.