AZI2

AZI2
Identifiers
Aliases	AZI2, AZ2, NAP1, TILP, 5-azacytidine induced 2
External IDs	OMIM: 609916; MGI: 1351332; HomoloGene: 8443; GeneCards: AZI2; OMA:AZI2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	28,349,050 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	118,069,794 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; monocyte; ; mucosa of paranasal sinus; ; Achilles tendon; ; buccal mucosa cell; ; gastric mucosa; ; right lung; ; lower lobe of lung; ; ganglionic eminence; ; ventricular zone;
	Top expressed in
	neural layer of retina; ; spermatid; ; genital tubercle; ; tail of embryo; ; spermatocyte; ; ventricular zone; ; dentate gyrus of hippocampal formation granule cell; ; parotid gland; ; atrioventricular valve; ; seminal vesicula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm;
Biological process	interleukin-6 production; dendritic cell differentiation; cytokine production; tumor necrosis factor production; interferon-alpha production; I-kappaB kinase/NF-kappaB signaling; T cell activation; dendritic cell proliferation; mitotic cell cycle; viral process;
	Sources:Amigo / QuickGO
Orthologs
	64343
	27215
	ENSG00000163512
	ENSMUSG00000039285
	Q9H6S1
	Q9QYP6
	NM_001134432; NM_001134433; NM_001271650; NM_022461; NM_203326
	NM_001048146; NM_001286507; NM_001286508; NM_013727
	NP_001127904; NP_001127905; NP_001258579; NP_071906
	NP_001041611; NP_001273436; NP_001273437; NP_038755
	Wikidata
View/Edit Human	View/Edit Mouse

5-azacytidine-induced protein 2 is a protein that in humans is encoded by the AZI2 gene.

AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003).[supplied by OMIM]