AP2A2

AP2A2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1B9K, 1KY6, 1KY7, 1KYD, 1KYF, 1KYU, 1QTP, 1QTS, 1W80, 2JKR, 2JKT, 2VJ0, 3HS8
Identifiers
Aliases	AP2A2, ADTAB, CLAPA2, HIP-9, HIP9, HYPJ, adaptor related protein complex 2 alpha 2 subunit, adaptor related protein complex 2 subunit alpha 2
External IDs	OMIM: 607242; MGI: 101920; HomoloGene: 5335; GeneCards: AP2A2; OMA:AP2A2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	1,012,245 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	141,212,924 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; spleen; ; superior frontal gyrus; ; sural nerve; ; right frontal lobe; ; subcutaneous adipose tissue; ; prefrontal cortex; ; canal of the cervix; ; pituitary gland; ; ganglionic eminence;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; neural layer of retina; ; dentate gyrus of hippocampal formation granule cell; ; stroma of bone marrow; ; CA3 field; ; medullary collecting duct; ; superior frontal gyrus; ; primary visual cortex; ; cerebellar cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	clathrin adaptor activity; protein binding; protein kinase binding; lipid binding; protein domain specific binding; disordered domain specific binding; molecular function;
Cellular component	endocytic vesicle membrane; cytosol; clathrin-coated endocytic vesicle membrane; membrane; plasma membrane; endolysosome membrane; membrane coat; clathrin-coated pit; AP-2 adaptor complex; clathrin adaptor complex; secretory granule membrane; cytoplasmic vesicle; ficolin-1-rich granule membrane; clathrin-coated endocytic vesicle;
Biological process	endocytosis; antigen processing and presentation of exogenous peptide antigen via MHC class II; ephrin receptor signaling pathway; mitigation of host defenses by virus; clathrin-dependent endocytosis; protein transport; intracellular protein transport; vesicle-mediated transport; microtubule-based movement; Wnt signaling pathway, planar cell polarity pathway; neutrophil degranulation; membrane organization; low-density lipoprotein particle receptor catabolic process; low-density lipoprotein particle clearance; transport;
	Sources:Amigo / QuickGO
Orthologs
	161
	11772
	ENSG00000281385; ENSG00000280759; ENSG00000183020
	ENSMUSG00000002957
	O94973
	P17427
	NM_001242837; NM_012305
	NM_007459; NM_001357068
	NP_001229766; NP_036437
	NP_031485; NP_001343997
	Wikidata
View/Edit Human	View/Edit Mouse

AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.