ANGPTL8

ANGPTL8
Identifiers
Aliases	ANGPTL8, PRO1185, PVPA599, RIFL, TD26, C19orf80, Betatrophin, angiopoietin like 8
External IDs	OMIM: 616223; MGI: 3643534; HomoloGene: 83285; GeneCards: ANGPTL8; OMA:ANGPTL8 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	11,241,943 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	21,748,643 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; gonad; ; subcutaneous adipose tissue; ; apex of heart; ; left coronary artery; ; epithelium of colon; ; muscle layer of sigmoid colon; ; tibial nerve; ; right adrenal cortex; ; right auricle of heart;
	Top expressed in
	left lobe of liver; ; tunica adventitia of aorta; ; white adipose tissue; ; tunica media of zone of aorta; ; brown adipose tissue; ; subcutaneous adipose tissue; ; right kidney; ; embryo; ; yolk sac; ; tail of embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; hormone activity;
Cellular component	extracellular region;
Biological process	regulation of lipid metabolic process; cell maturation; cellular lipid metabolic process; fat cell differentiation; positive regulation of protein processing; triglyceride homeostasis; lipid metabolism; regulation of lipoprotein metabolic process; regulation of lipoprotein lipase activity; type B pancreatic cell proliferation; regulation of signaling receptor activity; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	55908
	624219
	ENSG00000130173
	ENSMUSG00000047822
	Q6UXH0
	Q8R1L8
	NM_018687
	NM_001080940
	NP_061157
	NP_001074409
	Wikidata
View/Edit Human	View/Edit Mouse

ANGPTL8 (also known as lipasin, previously betatrophin) is a protein that in humans is encoded by the C19orf80 gene.