ACACB

ACACB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DN8, 2HJW, 2KCC, 3FF6, 3GID, 3GLK, 3JRW, 3JRX, 3TDC, 4HQ6, 5KKN
Identifiers
Aliases	ACACB, ACC2, ACCB, HACC275, acetyl-CoA carboxylase beta, ACC-beta, ACCbeta, ACACbeta
External IDs	OMIM: 601557; MGI: 2140940; HomoloGene: 74382; GeneCards: ACACB; OMA:ACACB - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	109,268,226 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	114,388,822 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; adipose tissue; ; subcutaneous adipose tissue; ; gastric mucosa; ; renal medulla; ; abdominal fat; ; pericardium; ; gastrocnemius muscle; ; muscle of thigh; ; apex of heart;
	Top expressed in
	brown adipose tissue; ; muscle of thigh; ; tunica adventitia of aorta; ; interventricular septum; ; right ventricle; ; myocardium of ventricle; ; intercostal muscle; ; skeletal muscle tissue; ; gastrocnemius muscle; ; extraocular muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; metal ion binding; biotin carboxylase activity; ligase activity; protein binding; catalytic activity; ATP binding; biotin binding; identical protein binding; acetyl-CoA carboxylase complex; acetyl-CoA carboxylase activity;
Cellular component	cytosol; membrane; mitochondrial outer membrane; mitochondrion; endomembrane system; nucleus;
Biological process	carnitine shuttle; malonyl-CoA biosynthetic process; negative regulation of catalytic activity; lipid metabolism; negative regulation of fatty acid oxidation; positive regulation of lipid storage; negative regulation of gene expression; fatty acid metabolic process; positive regulation of heart growth; negative regulation of fatty acid beta-oxidation; regulation of glucose metabolic process; fatty acid biosynthetic process; response to nutrient levels; energy homeostasis; metabolism; positive regulation of cellular metabolic process; negative regulation of lipid catabolic process; protein homotetramerization; acetyl-CoA metabolic process; response to organic cyclic compound; regulation of cholesterol biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	32
	100705
	ENSG00000076555
	ENSMUSG00000042010
	O00763
	E9Q4Z2
	NM_001093
	NM_133904
	NP_001084
	NP_598665; NP_001390456; NP_001390457; NP_001390458
	Wikidata
View/Edit Human	View/Edit Mouse

Acetyl-CoA carboxylase 2 also known as ACC-beta or ACC2 is an enzyme that in humans is encoded by the ACACB gene.