AB toxin

C2-like exotoxin "A" part
crystal structure of the enzymatic component of iota-toxin from clostridium perfringens with nadh
Identifiers
SymbolADPrib_exo_Tox
PfamPF03496
Pfam clanCL0084
InterProIPR003540
SCOP21giq / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
AB7-type toxin, "B" part
crystal structure of the anthrax toxin protective antigen heptameric prepore
Identifiers
SymbolBinary_toxB
PfamPF03495
InterProIPR003896
SCOP21acc / SCOPe / SUPFAM
TCDB1.C.42
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

The AB toxins are two-component protein complexes secreted by a number of pathogenic bacteria, though there is a pore-forming AB toxin found in the eggs of a snail. They can be classified as Type III toxins because they interfere with internal cell function. They are named AB toxins due to their components: the "A" component is usually the "active" portion, and the "B" component is usually the "binding" portion. The "A" subunit possesses enzyme activity, and is transferred to the host cell following a conformational change in the membrane-bound transport "B" subunit. T